|
|
L-aspartate + L-citrulline + ATP <=> H+ + argininosuccinate + diphosphate + AMP
|
6.3.4.5
argininosuccinate synthase
|
–
|
|
BRENDA:
BR142;
BS408483
KEGG:
R01954
MetaCyc:
ARGSUCCINSYN-RXN
SABIO-RK:
572
|
|
|
|
L-ornithine + Carbamoyl_phosphate <=> H+ + L-citrulline + phosphate
|
2.1.3.3
ornithine carbamoyltransferase
2.1.3.6
putrescine carbamoyltransferase
3.5.3.12
agmatine deiminase
|
–
–
–
|
|
BRENDA:
BR43950;
BS140887
KEGG:
R01398
MetaCyc:
ORNCARBAMTRANSFER-RXN;
RXN-13482
SABIO-RK:
98
|
|
|
|
argininosuccinate <=> L-arginine + fumarate
|
4.3.2.1
argininosuccinate lyase
4.3.2.2
adenylosuccinate lyase
|
–
–
|
|
BRENDA:
BR3431
KEGG:
R01086
MetaCyc:
ARGSUCCINLYA-RXN
SABIO-RK:
573
|
|
|
|
ATP + HCO3- + NH3 <=> ADP + phosphate + Carbamoyl_phosphate + H+
|
6.3.4.16
carbamoyl-phosphate synthase (ammonia)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
|
–
–
|
|
BRENDA:
BR137
KEGG:
R07641
MetaCyc:
RXN-13202
|
|
|
|
H2O + L-arginine <=> Urea + L-ornithine
|
3.5.3.1
arginase
3.5.3.7
guanidinobutyrase
|
–
–
|
|
BRENDA:
BR19260;
BS140960
KEGG:
R00551
MetaCyc:
ARGINASE-RXN
SABIO-RK:
574
|
|